Drug Metab Dispos

An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects Af

GR Tonn, SG Wong, SC Wong, MG Johnson, J Ma, R Cho, LC Floren, K Kersey, K Berry, AP Marcus, X Wang, B Van Lengerich, JC Medina, PG Pearson, and BK Wong. . Drug Metab Dispos. An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing. 2009; (37):502-13.

2009
https://researcherprofiles.org/profile/1330659

GR Tonn, SG Wong, SC Wong, MG Johnson, J Ma, R Cho, LC Floren, K Kersey, K Berry, AP Marcus, X Wang, B Van Lengerich, JC Medina, PG Pearson, and BK Wong.